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.arrow_box_above {position: relative;background: #FFF;border: 1px solid #A1A6B0;}
.arrow_box_above:after, .arrow_box_above:before {bottom: 100%;border: solid transparent;content: " ";height: 0;width: 0;position: absolute;pointer-events: none;}
.arrow_box_above:after {border-color: rgba(255, 255, 255, 0);border-bottom-color: #FFF;border-width: 10px;left: 3em;margin-left: -10px;}
.arrow_box_above:before {border-color: rgba(250, 250, 250, 0);border-bottom-color: #A1A6B0;border-width: 11px;left: 3em;margin-left: -11px;}
.comment_list .comm_header2 a{font-size: 0.85em;text-decoration:none;}
#comments_panel a{color: #2F4A8B;}
.comment_list .comm_content a{color: #767676;}
.comment_list .comm_content code, .comment_list .comm_content pre, #com_new_view code, #com_new_view pre{ font-family: inherit; font-size: inherit; }
.comment_list .comm_content pre { white-space: inherit; }
.comm_helpful{float:right;}
.comment_list .comm_helpful a{color: #2F4A8B; text-decoration:none;margin: auto 0.5em;}
.comment_list .comm_helpful a[class*='hlpfv']{color: #767676;}
.reply_indent{margin-left:8%;}
li.reply_indent{list-style: none outside none;}
li.reply_indent ul{margin-left: auto;min-height: 1em;padding-left: 0;margin-right:0em;}
.comment_list .comm_header .comm_votes{color:black;}
.recip_title{font-weight:bold;}
.recip_see{margin-right:3px;}
.recip_date{margin-left:1em;font-weight:normal;}
.comm_f_name,.comm_curr_commenter{font-weight:bold;}
.reply_cont, .replies_more{padding-left:0em;padding-top: 0.5em;}
.reply_hide{display:none;}
.comment_list li.comm_grp{border-top: none;margin-top: 1.3em;padding-top:0.8em;}
.comm_helpful{font-weight:bold;}
#com_tc_lk,#com_help_lk{padding-top:5px;}
.comment_list .comm_header2 span.comm_helpful{margin:0px;}
#coments_panel_anchor{float:right;margin-right:1em;}
#char_limit_msg{display:block;font-style:italic;}
.over_limit{color:rgb(168,74,58);}
.close_limit1{color:black;}
.in_limit{display:none;}
#com_tc , .ui-ncbipopper-wrapper {z-index: 200;}
#comm_cite_pop_inp{display:block;margin-top: 1em;}
#comm_cite_pop_inp:focus{outline:none;}
.comm_nlines{line-height:1.3846em;max-height:4.4em;overflow:hidden;}
.comm_hide_bad{margin-top:1em;display:block;}
.recip{margin:0.5em 0em;}
#comments_panel .comm_clipped_more{color: #767676;text-decoration: none;}
.ui-dialog .ui-dialog-buttonpane {text-align: center;}
#see_pmcommons{background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/4010017) no-repeat scroll transparent;display:none; padding-left: 1.5em; margin-bottom: 0.5em;color: #14376c;text-decoration: none;}
#author_preview span{margin-right:2em;}
#ap_content{font-size:1.2em;}
#ap_content a{color: #2F4A8B;text-decoration: none;}
#ap_head a{font-size:1.8em;}
#ap_content #ap_comm_count{font-size:1.4em;margin-right:0.3em;}
#ap_head{margin-bottom:1.5em; font-size: 1.2em;}
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.send_to .hint { }
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.display_settings li a { color: black; text-decoration: none; }
h4.content_header { margin-right: .2em;}
h4.send_to { float: right; _white-space: nowrap; }
.send_to .column_list { width: 20em; }
.disp_settings .column_list li { float: none; width: 9.5em; }
.sort .column_list li{width:13.5em;}
.format, .sort, .items { float: left; }
.format legend, .sort legend, .items legend, .send_to legend {font-weight:bold;margin: 2px 0 0 3px;}
.disp_settings { margin-left: 1em; _width:42em; }
div.results_settings{
    position:relative;  
    overflow:auto;width:100%;
}
ul.inline_list a{color: #2f4a8b;}
.results_settings .tgt_dark {
    background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/4016701) no-repeat scroll 100% 24.5% transparent;padding-right: 14px;
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    text-decoration:none;
}
ul.inline_list{padding-right:100px;}
.one_setting .disp_settings { _width:21em; }
.two_settings .disp_settings { _width:31em; }
.send_to { _width: 9em;}
.disp_settings button.button_apply { margin: 11em .5em .5em .8em;  }
.send_to .submenu { border-top: 1px solid #ddd; padding: 1em; margin:0; }
.send_to .submenu ul { margin: 0; padding:0; list-style-type:none; }
.send_to .submenu ul li { margin-bottom: .4em; }
.send_to .submenu ul li label { display: block; }
.send_to .hint { margin: .5em 0; }
.email_alert { background-color: #fcc; display: block;}
p#email_alert { display: none; }
p#email_alert.email_alert { background-color: #fcc; display: block;  }
p#email_alert.email_success {background-color: #dfd;}
div#send_to_menu , div#send_to_menu2 { width:330px; z-index: 200; }
.send_to .column_list li { width: 9.5em; }
.send_to .mail ul li span label { display: inline;}
.content_header_new1{color:black;}
ul.inline_list a{color: #2f4a8b;}
.results_settings .tgt_dark {
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}
ul.inline_list{padding-right:100px;}
.portlet { border-top: .4em solid #97b0c8; padding-top: .461em; margin: .769em 0 2.154em 0; overflow: visible; line-height: 1.231em; zoom:1; }
.portlet h1, .portlet h2, .portlet h3, .portlet h4, .portlet h5, .portlet h6 {color: #985735; font-weight: bold; display: inline;  }
.portlet .whatsthis {color: #14376c; white-space: nowrap; margin-left: .3em;}
.portlet ul { margin: 0; padding: 0; }
.portlet ul li { list-style-type: none; margin-top: .461em; border-bottom: 1px dotted #CCC; padding-bottom: 1px; position: relative; overflow: visible; zoom:1;  }
.portlet .portlet_list li { border-bottom: 0; }
.portlet ul li a { font-weight: normal; color: #14376c; text-decoration: none; }
.portlet ul li a:hover,.portlet ul li a:active{border-bottom:0}
.portlet ul a { _display: block; _float: left; _clear: left; }
.portlet .seemore { display: block; text-align: right; color: #14376c; font-size: .923em; text-decoration: none; margin-top: .8em; }
.portlet .portlet_section_header { text-decoration: none; font-weight: bold; color: #000; border-bottom:0 } 
.portlet li.two_line { height: 2.461em; height\0: 2.361em; overflow: hidden; }
.portlet .two_line a { max-height: 2.453em; overflow: hidden; display: block; }
.portlet .long_info, .portlet p, .portlet .two_line .source, .portlet .one_line_source, .portlet_content .image .desc, .portlet ul li .desc a { color: #777;}
.portlet .two_line .source, .portlet .one_line_source { white-space: nowrap; position: absolute; right: 0; background-color: white; padding-left: .3em; }
.portlet .two_line .source { top: 1.231em; }
.portlet .two_line .tertiary { font-size: .769em; color: #777; position: absolute; right:0; background-color: white; padding: .1em 0 0 .3em; top: 1.6em; top\0: 1.5em; }
.portlet .portlet_content p { margin: .8em 0; }
.portlet .buttonwrap { float: left; position: relative; top: -.1em; overflow: visible; }
.portlet .invert { color: #fff; background-color: #14376c; padding: 0 .2em; }
.portlet .tertiary { color: #777; text-align: right; line-height: 1.4em; position: relative; top: .1em; }
.portlet_content { position: relative; margin: 0; }
.portlet_content textarea { margin: 0 0 .9em; }
.portlet_content img { margin: .3em 1.4em .7em 0;}
.portlet_content .image { display: block; overflow: auto; overflow:hidden\0; }
.portlet_content .image .img_link { float: left; }
.portlet_shutter { background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/32197) no-repeat scroll left top;  display: block; float: right; width: 15px; height: 15px; position: absolute; top: -.2em; margin-left: .6em; right: 0; }
.shutter_closed { background-position: left bottom; }
.portlet .related li { border-bottom: 0; }
.portlet .right { text-align: right; }
.ra_qry, .ra_rcd { padding-left: 2em; }
.ra_qry { background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/32182) no-repeat scroll 0 1px; }
.ra_rcd { background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/32183) no-repeat scroll 0 1px; }
.sensor {border:1px solid #97B0C8;background-color:#FEFEFF;padding:0;margin:0 0 1em 0}
.sensor_inner {border:3px solid #D7E2EC;background-color:#FEFEFF;padding:0 1em 1em;margin:0}
.sensor .sensor_head { margin-bottom: 0; position: relative}
.sensor .sensor_head h3 { font-weight: normal; }
.sensor h3,.sensor h4,.sensor h5,.sensor h6{margin:.6923em 0 0}
.sensor .sensor_content{margin-bottom:1.1em}
.sensor p{margin:0}
.sensor .portlet_shutter { display: none; }
.no_p_margins{margin:0}
.portlet_head{margin-bottom:.461em;position: relative}
.portlet_title,.sensor_title{margin-right: 2em}
.portlet_title h3 { line-height: inherit; }
#ResultsHighlighter {  
    margin: .5em 0 1.0em;
    padding: .2em 0 .3em .4em;   
    background-color:#ffffdd;
    }
#ResultsHighlighter ul { 
    list-style-type: none; 
    padding: 0 1em; 
    margin: .4em 0 0 .3em;
}
li.highlight { margin: .2em 0em; }
 
li.highlight span.cit { 
    margin: .1em 0 .1em .5em; 
    color: #117;
    font-size: .9em;
} 
li.highlight span.cit abbr {
    border: none;
    font-style:italic;
}
#ResultsHighlighter h2, #CSResultsHeader h2 { 
    color: #444; 
    font-size: 1em;
    padding-bottom: .2em;
    margin: 0 auto;
}
#ResultsHighlighter span.all {
    float:right;
    clear:left;    
    padding-right:1em; 
}
#CSResultsHeader {  
    font-size: .9em; 
    margin: .5em 0 0 0;
    padding: .2em 0 .3em .4em;  
}
h3.result_count { display:inline; white-space:nowrap; margin: 0 0 2em;}
.result_sel { margin-left: 1em;white-space:nowrap;float: left;}
.clip_actions { margin-bottom: 1.3em; }
.clip_action { color: #D2692B;text-decoration: none; border-bottom: 1px dotted #D2692B; margin-left: 1em; white-space:nowrap; float:left;}
.sensor_inner .messages {margin-top:1em;}
.sensor_inner > p > .details{margin-left:3px;}
#LimitsMsg .limits_links { margin-left: 1em; font-size: 0.846em; white-space: nowrap; }
div.success_msg, div.warn_msg, div.error_msg { padding: .4em; margin: .5em; color: black; font-family: helvetica, arial, verdana, sans-serif; }
div.success_msg img, div.warn_msg img, div.error_msg img { position: relative; top: .15em; margin-left: .2em; }
div.success_msg { border: 1px solid #6c6; background-color: #cfc; }
div.warn_msg { border: 1px solid #e3d21c; background-color: #ffffef; }
div.error_msg { border: 1px solid #f88; background-color: #fdd; }
div.messagearea {
    margin:0;
    padding: 0;
    clear:both;
}
div.browsername {
    background-color: #FFF;
    padding-left: 0.5em;
    }
#messagearea.empty {
    border: none;
    clear: both;
}
div#messagearea ul.messages li.hi_warn { margin: 2.5em 0; }
ul.messages {
    font-family: arial, helvetica, sans-serif;
    margin: 0;
    padding: 0;
    list-style-type: none;
    list-style-image: none;
}
ul.messages li {
    margin: 0.22em 0 0.22em;
    padding: 0.25em;
    background: transparent no-repeat 0.5em 0.3em;
    position: relative;
}
ul.messages li .icon, ul.messages li.icon{ 
    background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/3797312) no-repeat; 
    display: block; 
    margin-right: 4px;
    padding-left: 16px;
}
ul.messages li span.icon {
    background: #fff;
    padding-left: .5em;
    padding-top: .35em;
    margin-top: -.5em;
}
ul.messages li.success .icon, ul.messages li.success.icon {
    background-position: 0 0;
}
ul.messages li.warn .icon, ul.messages li.hi_warn .icon, ul.messages li.warn.icon, ul.messages li.hi_warn.icon {
    background-position: -17px 0;
}
ul.messages li.suggest .icon, ul.messages li.suggest.icon {
    background-position: -34px 0;
}
ul.messages li.info .icon, ul.messages li.info.icon {
    background-position: -51px 0;
}
ul.messages li.error .icon, ul.messages li.error.icon {
    background-position: -68px 0;
}
ul.messages li.hi_warn em.detail{
    font-weight: normal;
    font-style: normal;
    padding-left: 1.7em;
}
ul.messages li.hi_warn {
    font-weight: bold;
}
.success, .error, .warn, .info, .suggest, .hi_warn {
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    padding-left: 17px;
    background-repeat: no-repeat;
    background-color: transparent;
    margin-bottom:.5em
}
.success {
    background-position: 0 0;
}
.warn {
    background-position: -17px 0;
}
.hi_warn {
    background-position: -17px 0;
    font-weight: bold;
}
.suggest {
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}
.info {
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}
.error {
    background-position: -68px 0;
}
.rprt {
	overflow: hidden;
	_overflow: none;
	margin: 0.5em 0 1.5em 0;
	padding: 0; 
	*margin-bottom: 0.9em;
	zoom: 1;
	display: block;
	clear: both;
	min-height: 40px;
	height: auto !important;
	height: 40px; }
.rprt .rprtnum {
	display: inline;
	float: left;
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.rprt .rprtnum input {
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.rprt .rprtnum span {
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	margin-right: 5px;
	margin-left: 1px; 
	*margin-left: 4px; }
.rprt .rslt { margin-left: 28px; *height: 1%; *margin-left: 0; }
.rprt .rsltimg { float: left; }
.rprt .rsltimg_right { float: right; margin-right: 0; margin-left: 1em;}
.rprt .rsltimg img {
	width: 100px;
	border: #666 solid 1px;
	padding: 1px; }
.rprt .rsltimg + .rsltcont { padding-left: 120px; }
.rprt .rsltimg_right + .rsltcont { padding-left: 0; }
.rprt .title {
	font-size: 1.108em;
	margin: 0; }
.rprt .title a { color: #2222cc; }
.rprt .title a:visited { color: #642a8f; }
.rprt .supp { margin: .1425em 0; }
.rprt .supp p, .rprt .supp dl, .rprt .supp dt, .rprt .supp dd { margin: 0; }
.rprt .supp .desc {
	font-size: 1.077em;
	display: block; }
.rprt .supp .details {
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.rprt dl{margin:0}
.rprt dl dt, .rprt dl dd {
	display: inline;
	padding: 0;
	margin: 0; }
.rprt dl dt { margin-left: .5em !important; }
.rprt dl dt:first-child { margin-left: 0 !important; }
.rprt dl.details { _margin-left: -.5em !important; }
.rprt dl dd, .rprt dl dt { white-space: nowrap; }
.rprt dl.lefty{display:block}
.rprt dl.lefty dt{width:10em;display:table-cell}
.rprt dl.lefty dd{display:table-cell}
.rprt dl.butterfly{display: block;margin:0;clear:both}
.rprt dl.butterfly dt{width: 10em; float: left; clear: left; text-align: right; margin-right: 10px;  }
.rprt dl.butterfly dd{margin: 0 0 0 10em; clear: right; }
	
.rprt .aux { font-size: 0.923em; }
.rprt .aux .status_icon, .rprt .aux .links a { white-space: nowrap; }
.rprt .aux, .rprt .aux p, .rprt .aux dl {
	margin-top: 0;
	margin-bottom: 0;
	line-height: 1.4em;  }
.rprt .aux .resc { color: #575757; }
.rprt .aux .status_icon {
	color: #985735;
	font-weight: bold; }
.rprt .aux .src {
	margin-right: 15px;
	display: inline; }
.rprt .aux .rprtid {
	color: #575757;
	display: inline;
	margin-right: 15px; }
.rprt .aux .links a {
	text-decoration: underline;
	cursor: pointer;
	margin-right: 15px;
	color: #6666AA;
	white-space: nowrap; }
.rprt .aux .links .in_clip {
	margin-right: .5em;
	color: #D2692B;
	white-space: nowrap; }
.rprt .aux .links .rem_clip {
	margin-right: .5em;
	color: #D2692B;
	text-decoration: none;
	border-bottom: 1px dotted #D2692B;
	white-space: nowrap; }
.rprt .dblinks {
	margin-top: 0em;
	margin-bottom: 0em;
	line-height: 1.334em; }
.rprt .dblinks a {
	text-decoration: none;
	cursor: pointer;
	white-space: nowrap;
	color: #6666AA; }
.rprt .dblinks a:hover { text-decoration: underline; }
.rprt p.title a {
	_position: relative;
	_left: -.15em; }
.rprt-button { float: right }
.rprt-button span { margin: 0.231em 0.462em 0.462em -0.462em }
.rprt-supplinks { padding: 0.461em 0 }
.rprt-supplinks h5 { margin: 0.231em 0 }
.rprt-supplinks p { margin-top: 0 }
.rprt-supplinks .rprt-seeall {
    text-align: right;
    font-size: 0.846em;
    margin: 0; }
.rprt-separator {
    border-style: none;
    font-size: 0;
    height: 1px;
    margin: -1px 0;
    opacity: 0;
    position: relative; }
.ncbi_carousel{ background-color: #f2f5f8;
    border: 1px solid #9bb0c8;
    margin: 1em 0;
    overflow: hidden;
    padding-top: 0.1em;
    position: relative;
} 
.ncbi_carousel .nc_header{margin:auto auto 5px 5px;}
.ncbi_carousel .nc_content{position:relative;
    min-width: 300px;
    overflow: hidden;
    padding-top: 0.1em;
    height:200px;
}
.ncbi_carousel .nc_item {position:absolute;top:2px;border: 1px solid #14376c;}
.ncbi_carousel .nc_arrow {
    border-bottom: medium none;
    height: 250px;
    width: 20px;
    position: absolute;
    top: 20px;
    z-index:100;
    opacity: 0.4;
}
.ncbi_carousel .nc_arrow_left {
    background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/252363) no-repeat scroll left center transparent;
    left: 0;
}
.ncbi_carousel .nc_arrow_right {
    background: url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/252362) no-repeat scroll right center transparent;
    right: 0;
}
.ncbi_carousel .nc_arrow_inactive {
    cursor: default;
    opacity: 0.1;
}
.ncbi_carousel .nc_arrow_highlight{
    opacity: 1;
}
.ncbi_carousel .nc_toggler{
    position:absolute;
    right:0;
    background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/32197) no-repeat top right;
    padding-right:20px;
    text-decoration: none;
}
.ncbi_carousel .nc_toggler_open{
    
}
.ncbi_carousel .nc_toggler_closed{
    background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/32197) no-repeat bottom right;
}
div.rprt_all{width:100%}
.abstract.rprt { padding-bottom: 0.5em; }
.abstract h1 { font-size: 1.231em; font-weight: bold; line-height: 1.125em; margin: .375em 0; }
.abstract h1 a { font-weight: bold; } 
.abstract p { margin: .5em 0; }
.abstract a { color: #333; border-bottom: 0; text-decoration: underline; }
.abstract a:hover { color: #2222CC; border-bottom: 0; }
.abstract a:visited { color: #606; border-bottom: 0; }
.abstract a.jig-ncbitoggler, .abstract a.jig-ncbitoggler:hover { text-decoration: none !important; }
.abstract a.ui-ncbitoggler, .abstract a.ui-ncbitoggler-open { padding-left: 1.75em; }
.abstract a.ui-ncbitoggler span.ui-icon-triangle-1-e { background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/29039) no-repeat left -30px; }
.abstract a.ui-ncbitoggler-open span.ui-icon-triangle-1-s  { background: transparent url(//static.pubmed.gov/portal/portal3rc.fcgi/4082458/img/29039) no-repeat left 0; }
.abstract a.ui-ncbitoggler {  }
.abstract a.ui-ncbitoggler:hover { color: #777; }
.abstract .err h3, .morecit h4 { margin: .5em 0 0 0 !important; display: block; color: #000; }
.abstract .err ul { margin: 0 0 .5em; list-style-type: none; padding:0; }
.abstract .err li { display: block; }
.abstract .err .comments a { color: #14376C; text-decoration: none; }
.abstract .err .comments .source { padding-left: 0.3em; color: #777777; }
.abstract .err .comments em.author { font-size: 0.8465em; line-height: 1.3em; display: block; margin-bottom: -0.3em; margin-top: 0.5em; }
.abstract .err .comments em.cit { font-size: 0.8465em; line-height: 1.3em; display: block; margin-bottom: -0.3em; margin-top: 0.5em; }
.abstract .err { margin: 1.1em auto 0; }
.abstract .abstr h3, .abstract .sections h3 {color:#985735; font-weight:bold; margin: 0; ;}
.abstract .sections ul {list-style:none;padding:0px;margin-top:0px;margin-left:0;}
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